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Change in Pregnancy Disclosure for Adolescents 12 and Under

Section 2.4.2 of SOP 4801 has been revised to remove the reference to disclosure of pregnancy to a minor’s parents if the child is 12 years or younger. Read more…

UNC Awarded “Gold Seal” of Accreditation for Human Research Protection Program

The University of North Carolina at Chapel Hill’s Human Research Protection Program has been awarded full reaccreditation by the Association for the Accreditation of Human Research Protection Programs (AAHRPP) for an additional five years. We were reaccredited in June 2023, following a two-day on-site evaluation in March 2023. Read more…

Change in OHRE’s CITI Training Verification Procedure

The Office of Human Research Ethics (OHRE) and the Institutional Review Board (IRB) will no longer verify CITI Training for the PI or research team members at the time of Continuing Review or Administrative Review. Read more…

Introduction to Human Research Subject Protection at UNC

Last year, over one million people took part in research studies at UNC-Chapel Hill. Who are these participants, who is studying them and why?

Organizational Structure

The Office of Human Research Ethics (OHRE) is responsible for ethical and regulatory oversight of research at the University of North Carolina at Chapel Hill that involves human subjects. OHRE supports and oversees the work of the Institutional Review Boards (IRBs).

IRB Boards A through F review research in a wide variety of areas:

  • Biomedical Research: School of Medicine, School of Pharmacy, UNC Hospitals, and research in other units that involves biomedical interventions. Expertise is focused on medical, surgical, physiological or pharmacological studies. Includes research with drugs, devices, counseling, or other interventions. Studies that require dental or oncology expertise are reviewed by Biomedical Boards B or D.
  • Behavioral and Public Health-Nursing Research: such as psychology, child development, education, anthropology, information and library science, social work, journalism, and many other disciplines under Academic Affairs, as well as studies from the School of Public Health, School of Nursing, nursing-related studies at UNC Hospitals, non-medical research from the Injury Prevention Research Center, Carolina Population Center, Health Promotion Disease Prevention, and Sheps Center. Expertise is focused on research in behavioral and social sciences, the humanities, epidemiology and other research in a public health or nursing context.
  • As well as expertise in reviewing Unanticipated Problems Involving Risks to Subjects or Others (UPIRSO) and other compliance issues, Humanitarian Use Devices (HUDs), emergency research on single patients under a single subject treatment IND.