IRB and Office of Human Research Ethics

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  • March 2, 2015: The Online Submission Guide has been substantially updated and expanded.
  • February 6, 2015: We have revised the IRBIS investigator interface to provide improved search/filter functionality.  Click here to see a two-page summary of the changes.
  • For older items, see News section

Organizational Structure

The Office of Human Research Ethics (OHRE) is responsible for ethical and regulatory oversight of research at the University of North Carolina at Chapel Hill that involves human subjects. OHRE supports and oversees the work of the Institutional Review Boards (IRBs). The IRBs at the University of North Carolina at Chapel Hill are organized by area of expertise.  The IRBs are:

Biomedical IRB (Committees A through D) Reviews research involving School of Medicine, School of Pharmacy, UNC Hospitals, and research in other units that involves biomedical interventions. Expertise is focused on medical, surgical, physiological or pharmacological studies. Includes research with drugs, devices, counseling, or other interventions. Studies that require dental expertise are reviewed by Biomedical Committee B.

Non-Biomedical IRB (Committee E)  A combination of the former Behavioral and Public Health-Nursing IRBs. Reviews research in psychology, child development, education, anthropology, information and library science, social work, journalism, and many other disciplines under Academic Affairs, as well as studies from the School of Public Health, School of Nursing, nursing-related studies at UNC Hospitals, non-medical research from the Injury Prevention Research Center, Carolina Population Center, Health Promotion Disease Prevention, and Sheps Center. Expertise is focused on research in behavioral and social sciences, the humanities, epidemiology and other research in a public health or nursing context.


CB 7097
Medical School Bldg. 52
105 Mason Farm Road
Chapel Hill, NC 27599-7097

Ph: 919-966-3113
Fax: 919-966-7879

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