1 |
AHCTF1 |
Mixed |
2266 |
Pan-cancer |
2 |
AMBRA1 |
WD40 |
1298 |
Pan-cancer |
3 |
ATG16L1 |
WD40 |
607 |
IBD, Diabetes |
4 |
ATRN |
KELCH |
1429 |
Kidney Cancer |
5 |
BBS1 |
PQQ |
593 |
Bardet-Biedl Syndrome |
6 |
BRWD3 |
WD40 |
1802 |
MENTAL RETARDATION, X-LINKED 93 (disorder) |
7 |
CDC20 |
WD40 |
499 |
Brain Cancers |
8 |
CIAO1 |
WD40 |
339 |
Pan-cancer |
9 |
CLTC |
Clathrin |
1675 |
Pan-cancer |
10 |
COP1 |
WD40 |
731 |
Immuno-oncology |
11 |
COPA |
WD40 |
1224 |
AUTOIMMUNE INTERSTITIAL LUNG, JOINT, AND KIDNEY DISEASE |
12 |
CORO1A |
WD40 |
461 |
IMMUNODEFICIENCY 8 |
13 |
CPSF1 |
WD40 |
1443 |
Pan-cancer |
14 |
DMXL1 |
WD40 |
3027 |
Pan-cancer |
15 |
DPP6 |
PeptidaseS9 |
865 |
MENTAL RETARDATION, AUTOSOMAL DOMINANT 33 |
16 |
DYNC2I1 |
WD40 |
1066 |
Jeune thoracic dystrophy |
17 |
DYNC2I2 |
WD40 |
536 |
Jeune thoracic dystrophy |
18 |
EED |
WD40 |
441 |
COHEN-GIBSON SYNDROME |
19 |
EMC1 |
PQQ |
993 |
CEREBELLAR ATROPHY, VISUAL IMPAIRMENT, AND PSYCHOMOTOR RETARDATION |
20 |
EML1 |
Mixed |
815 |
BAND HETEROTOPIA |
21 |
FBXW11 |
WD40 |
542 |
Colorectal, Gastic Cancers |
22 |
FBXW7 |
WD40 |
707 |
Ovarian |
23 |
FZR1 |
WD40 |
496 |
Ovarian Cancer |
24 |
GEMIN5 |
Mixed |
1508 |
Pan-cancer |
25 |
GLDN |
Olfactomedin |
551 |
LETHAL CONGENITAL CONTRACTURE SYNDROME 11 |
26 |
GNB1 |
WD40 |
340 |
GNB1 Encephalopathy |
27 |
GNB3 |
WD40 |
340 |
Childhood Obesity; Hypertension; type 2 diabetes |
28 |
GNB4 |
WD40 |
340 |
CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE F |
29 |
GNB5 |
WD40 |
395 |
LANGUAGE DELAY AND ATTENTION DEFICIT-HYPERACTIVITY DISORDER/COGNITIVE IMPAIRMENT WITH OR WITHOUT CARDIAC |
30 |
GRWD1 |
WD40 |
446 |
Ovarian |
31 |
HERC1 |
Mixed |
4861 |
MACROCEPHALY, DYSMORPHIC FACIES, AND PSYCHOMOTOR RETARDATION |
32 |
IFT80 |
WD40 |
777 |
Jeune thoracic dystrophy |
33 |
ITGAV |
Mixed |
1048 |
Breast, Colorectal, and Lung Cancers |
34 |
KATNB1 |
WD40 |
655 |
Pancreatic Cancer |
35 |
KBTBD2 |
KELCH |
623 |
Ewing Sarcoma, Bone Cancer |
36 |
KEAP1 |
KELCH |
624 |
Non-small cell lung cancer |
37 |
KIF21A |
WD40 |
1674 |
Fibrosis Of Extraocular Muscles, Congenital, 1 |
38 |
KLHL24 |
KELCH |
600 |
Epimermolysis Bullosa |
39 |
KNTC1 |
WD40 |
2209 |
Colorectal, Gastic Cancers |
40 |
LRP2 |
Mixed |
4655 |
Donnai-Barrow syndrome |
41 |
LRP8 |
Mixed |
963 |
Blood Cancers |
42 |
LZTR1 |
KELCH |
840 |
Noonan Syndrome 2 |
43 |
MAPKBP1 |
WD40 |
1514 |
NEPHRONOPHTHISIS 20 |
44 |
MED16 |
Mixed |
877 |
Haematopoietic And Lymphoid Cancers |
45 |
MEGF8 |
KELCH |
2845 |
CARPENTER SYNDROME 2 |
46 |
MET |
Mixed |
1390 |
Central Nervous System Cancers |
47 |
MMP2 |
Hemopexin |
660 |
TORG-WINCHESTER SYNDROME |
48 |
MMP20 |
Hemopexin |
483 |
Amelogenesis Imperfecta, Hypomaturation Type, Iia2 |
49 |
MMP25 |
Hemopexin |
562 |
Inflammation |
50 |
NBAS |
WD40 |
2371 |
Developmental delay (disorder) |
51 |
NEU1 |
Sialidases |
415 |
Type I Mucolipidosis, Inflammation |
52 |
NLE1 |
WD40 |
485 |
Pan-cancer |
53 |
NOL11 |
WD40 |
719 |
Pan-cancer |
54 |
NUP133 |
WD40 |
1156 |
NEPHROTIC SYNDROME, TYPE 18 |
55 |
PAFAH1B1 |
WD40 |
410 |
Miller-Dieker syndrome |
56 |
PAK1IP1 |
WD40 |
392 |
Gastric Cancer |
57 |
PALB2 |
WD40 |
1186 |
Reproductive Cancers; Cancers with reversions in BRCA2 |
58 |
PDCL |
Phosducin |
301 |
Skin and Kidney Cancers |
59 |
PHIP |
WD40 |
1821 |
DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES |
60 |
PLXNC1 |
Mixed |
1568 |
Inflammation |
61 |
PRG4 |
Hemopexin |
1404 |
CAMPTODACTYLY-ARTHROPATHYCOXA VARA-PERICARDITIS SYNDROME |
62 |
PRPF4 |
WD40 |
522 |
RETINITIS PIGMENTOSA 70 |
63 |
RACK1 |
WD40 |
317 |
Osteoperosis; Bone Loss |
64 |
RAE1 |
WD40 |
368 |
Pan-cancer |
65 |
RAG2 |
KELCH |
527 |
Severe Combined Immunodeficiency |
66 |
RBBP4 |
WD40 |
425 |
Colorectal, Gastic Cancers |
67 |
RBBP7 |
WD40 |
425 |
Pan-cancer; Neurodegeneration |
68 |
RFWD3 |
WD40 |
774 |
Ovarian Cancer |
69 |
RPGR |
RCC1 |
1020 |
Retinitis Pigmentosa |
70 |
RPTOR |
WD40 |
1335 |
Pan-cancer |
71 |
RRP9 |
WD40 |
475 |
Gastric Cancer |
72 |
SCAP |
WD40 |
1279 |
Hypertriglyceridemia; Hyperlipidemia; Pan-cancer |
73 |
SEC31A |
WD40 |
1220 |
Lung Cancers (SEC31A-ALK fusions) |
74 |
SEC31A |
WD40 |
1220 |
Lymphomas |
75 |
SEH1L |
WD40 |
360 |
Gastric Cancer |
76 |
TAF1C |
WD40 |
869 |
Pan-cancer |
77 |
TAF5 |
WD40 |
800 |
Skin Cancer |
78 |
THOC6 |
WD40 |
341 |
Breast and Esophogael Cancers |
79 |
TRIM2 |
NHL |
744 |
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2R |
80 |
UBR4 |
WD40 |
5183 |
Pan-cancer |
81 |
UTP18 |
WD40 |
556 |
Pan-cancer |
82 |
VPS39 |
Clathrin |
886 |
Blood Cancers |
83 |
WDHD1 |
WD40 |
1129 |
Pan-cancer |
84 |
WDR1 |
WD40 |
606 |
Blood Cancer, Head and Neck Cancers |
85 |
WDR11 |
WD40 |
1224 |
HYPOGONADOTROPIC HYPOGONADISM 14 WITH OR WITHOUT ANOSMIA |
86 |
WDR18 |
WD40 |
432 |
Lung Cancers |
87 |
WDR24 |
WD40 |
790 |
Ovarian Cancer |
88 |
WDR25 |
WD40 |
544 |
Pan-cancer |
89 |
WDR26 |
WD40 |
661 |
Ovarian Cancer |
90 |
WDR36 |
WD40 |
951 |
Breast and Pancreatic Cancers |
91 |
WDR45 |
WD40 |
360 |
Beta-propeller protein-associated neurodegeneratio |
92 |
WDR48 |
WD40 |
677 |
Ovarian and Uterine Cancers |
93 |
WDR7 |
Mixed |
1490 |
Head and Neck Cancer |
94 |
WDR72 |
WD40 |
1102 |
Amelogenesis Imperfecta, Hypomaturation Type, Iia3 |
95 |
WDR73 |
WD40 |
378 |
Ovarian Cancer |
96 |
WDR77 |
WD40 |
342 |
MTAP-deleted cancers |
97 |
WDR82 |
WD40 |
313 |
Pan-cancer |
98 |
WDR83 |
WD40 |
315 |
Pan-cancer |
99 |
WRAP73 |
WD40 |
460 |
Haematopoietic And Lymphoid Cancers |
100 |
WSB2 |
WD40 |
404 |
Skin, Liver, Thyroid Cancers |