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Ledger 4 Clinical Trial Guidance

In order to facilitate timely monitoring and closeouts for Ledger 4 clinical trials, the Office of Sponsored Research (OSR) has implemented a new process for Ledger 4 date change requests. This process is outlined in the Ledger 4 Clinical Trial Guidance located on the OSR Resources webpage. This document provides details on the process for requesting a date extension or changing the date to start the closeout process. This guidance only applies to Ledger 4 clinical trials.

Key Elements for Ledger 4 Closeout:


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