Unit Type: Core Facilities

The university shRNA core is premised on Open Biosystems TRC1 shRNA libraries. The libraries are catalogued as a single lentiviral-vector shRNA expression clones directed to ~16000 human and mouse genes.

The primary objective of our facility is to produce monoclonal antibody-producing hybridoma cell lines for UNC investigators.

The UNC hESC Core Facility aims to provide support for UNC investigators working with human embryonic stem cells by providing training in laboratory protocols and techniques for hESC propagation and culture, and access to necessary equipment and laboratory space to enhance translational and clinical research.

The Histology Facility in the Department of Cell and Molecular Physiology is designed to provide expertise and consultation on histological and immunohistochemical methods.

The UNC-CH Genome Analysis Facility (formerly the UNC-CH Automated DNA Sequencing Facility) is a Core Facility, established in 1992 by the Program in Molecular Biology and Biotechnology (PMBB), to provide researchers at The University of North Carolina at Chapel Hill with access to state-of-the-art resources for DNA sequencing and genotyping.

The Functional Genomics Core provides expression profiling and SNP genotyping (Affymetrix) services.

The UNC Flow Cytometry Facility provides state-of-the-art flow cytometry and related services to the entire UNC-CH research community as well as to others in the Research Triangle Park area.

The Goal of the UNC CFAR Clinical Pharmacology and Analytical Chemistry (CPAC) Core is to Provide Comprehensive Study Design, Bioanalytical, and Data Analyses Support to Animal and Human Clinical Pharmacology Investigations in the HIV/AIDS arena.

The nutrition research and metabolism core provides three primary services to investigators: metabolic diets and controlled nutrient research cababilities, research dietitians skilled in nutrition research methods, and body composition measurements that meet precision requirements for research.

Clinical services are provided by highly-skilled, versatile nurses and certified phlebotomy staff.