The Children’s Research Institute “Single-Cell RNA sequencing reveals Chlamydia trachomatis-driven T cell activation and differentiation in cervical mucosal immunity”

Dr. Zheng is a multidisciplinary scientist specializing in systems immunology of infectious diseases and vaccines, human genetics, and biostatistics. Currently a Professor in the Department of Pediatrics at the University of North Carolina at Chapel Hill, she has extensive experience working with large infectious disease cohorts and conducting multi-omics data analyses. Her primary interest lies in identifying protective systemic blood and local mucosal cellular immune responses as well as antibody responses against bacterial or viral infections and diseases. To address the challenges of multi-level omics and multi-cohort data analysis, her team has developed a series of new statistical methods for causal network analysis, causal mediation analysis, digital immune cell separation, rigorous multi-study normalization and batch effect correction, and integrative single cell sequencing (scRNA-seq) and bulk RNA-seq data analysis.

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